Endoplasmic reticulum stress-related genes drive M1 macrophage polarization in preeclampsia via modulating metabolic reprogramming: a bioinformatic study
HTRA1, GBA1, KL, and PC may serve as diagnostic biomarkers for PE, potentially influencing M1 polarization of placental macrophages via metabolic reprogramming.
Authors
- Hui Xu (ORCID: https://orcid.org/0000-0001-5517-3556)
- Chunzi Xu
- Yue Lu (ORCID: https://orcid.org/0000-0002-5479-9095)
- Xu Huang (ORCID: https://orcid.org/0000-0002-8882-4287)
- Ling Gu (ORCID: https://orcid.org/0000-0002-3368-4053)
- Ruikun Hu
Institutions
- Nantong University (CN)
- Nantong Maternity and Child Health Hospital (CN)
- Reproductive Genetics Institute (US)
Publication Details
- Journal
- Hypertension in Pregnancy
- Published
- 2026-03-26
- DOI
- https://doi.org/10.1080/10641955.2026.2649740
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00