Preventive Effects of <i>trans</i> ‐4‐Methoxy‐β‐nitrostyrene on Monocrotaline‐Induced Pulmonary Arterial Hypertension in Rats

Taken together, the present study provided the first evidence that T4MN prevents the development of MCT-induced HAP in rats. Further mechanistic studies of these protective effects of T4MN are warranted.

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Publication Details

Journal
Fundamental and Clinical Pharmacology
Published
2026-03-26
DOI
https://doi.org/10.1111/fcp.70078
Primary Topic
Pulmonary Hypertension Research and Treatments
Type
article
Field-Weighted Citation Impact
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article

Preventive Effects of trans ‐4‐Methoxy‐β‐nitrostyrene on Monocrotaline‐Induced Pulmonary Arterial Hypertension in Rats

Alexandre Havt, Armênio Aguiar dos Santos, A. A. Alves, Karoline Gonzaga‐Costa et al.
Fundamental and Clinical Pharmacology
Pulmonary Hypertension Research and Treatments
article

Preventive Effects of trans ‐4‐Methoxy‐β‐nitrostyrene on Monocrotaline‐Induced Pulmonary Arterial Hypertension in Rats

Alexandre Havt, Armênio Aguiar dos Santos, A. A. Alves, Karoline Gonzaga‐Costa, Rodrigo José Bezerra de Siqueira, Davi Benevides Almeida, Glória Pinto Duarte, Liova Chabot Díaz, Yeimer Antonio Santiago Guevara, Pedro Jorge Caldas Magalhaes, Saad Lahlou, Matyelle Jussára Rodrigues‐Silva, Marcus Lins Queiroga, Renata Fereirra Carvalho Leitão, Rosivaldo Santos Borges
article en

Abstract

Taken together, the present study provided the first evidence that T4MN prevents the development of MCT-induced HAP in rats. Further mechanistic studies of these protective effects of T4MN are warranted.

Fundamental and Clinical PharmacologyVol. 40(3)
Universidade Federal do Ceará (BR), Universidade Federal de Pernambuco (BR), Universidade Federal do Pará (BR)
Good health and well-being
Openalex Percentile: Top 7%
Pulmonary Hypertension Research and Treatments
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Preventive Effects of <i>trans</i> ‐4‐Methoxy‐β‐nitrostyrene on Monocrotaline‐Induced Pulmonary Arterial Hypertension in Rats — Alexandre Havt, Armênio Aguiar dos Santos, et al. · Fundamental and Clinical Pharmacology (2026) | TGRS Research Map | TGRS