HLA Allelic and Haplotypic Organization in Common ABO Blood Group Phenotypes: A Single-Center Cross-Sectional Analysis

The analysis indicated that A Rh(+) and O Rh(+) donors share a largely similar HLA genetic background, with modest but detectable differences in selected HLA alleles and LD patterns. These subtle variations likely reflect minor population heterogeneity rather than distinct ancestry and may aid donor matching and interpretation of population-based immunogenetic association studies.

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Publication Details

Journal
Turkish Journal of Hematology
Published
2026-03-26
DOI
https://doi.org/10.4274/tjh.galenos.2026.99267
Primary Topic
Blood groups and transfusion
Type
article
Field-Weighted Citation Impact
0.00
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article

HLA Allelic and Haplotypic Organization in Common ABO Blood Group Phenotypes: A Single-Center Cross-Sectional Analysis

Emel Yantır, Eren Gündüz
Turkish Journal of Hematology
Blood groups and transfusion
article

HLA Allelic and Haplotypic Organization in Common ABO Blood Group Phenotypes: A Single-Center Cross-Sectional Analysis

Emel Yantır, Eren Gündüz
article en

Abstract

The analysis indicated that A Rh(+) and O Rh(+) donors share a largely similar HLA genetic background, with modest but detectable differences in selected HLA alleles and LD patterns. These subtle variations likely reflect minor population heterogeneity rather than distinct ancestry and may aid donor matching and interpretation of population-based immunogenetic association studies.

Turkish Journal of Hematology
Eskişehir Osmangazi University (TR)
Openalex Percentile: Top 6%
Blood groups and transfusion
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