Pulmonary Squamous Cell Carcinoma Presenting as Glenoid Bone Metastasis: A Case Report

We present the case of a 64-year-old male patient who reported right shoulder radiculopathy, right-hand weakness, and 3 kg weight loss. Physical examination revealed restricted active shoulder mobility. Magnetic resonance imaging showed a massive septated lesion in the glenoid that infiltrated adjacent tissues, indicating sarcoma. Core needle biopsy revealed metastatic poorly differentiated squamous cell cancer. Positron emission tomography scan results showed a primary lung tumor (stage IVB) with metastases to the left adrenal gland and a large mass in the right glenoid. This case describes the first documented case of metastatic lung squamous cell carcinoma to the shoulder glenoid, an uncommon metastatic location.

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Publication Details

Journal
Orthopedics
Published
2026-03-01
DOI
https://doi.org/10.3928/01477447-20260216-02
Primary Topic
Management of metastatic bone disease
Type
article
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article

Pulmonary Squamous Cell Carcinoma Presenting as Glenoid Bone Metastasis: A Case Report

Mohamad Nassereddine, Saïd Saghieh, Jad M. El Abiad, Anas El Zouhbi et al.
Orthopedics
Management of metastatic bone disease
article

Pulmonary Squamous Cell Carcinoma Presenting as Glenoid Bone Metastasis: A Case Report

Mohamad Nassereddine, Saïd Saghieh, Jad M. El Abiad, Anas El Zouhbi, Anthony Shebly, Michael Daaboul, Safaa Zakleet
article en

Abstract

We present the case of a 64-year-old male patient who reported right shoulder radiculopathy, right-hand weakness, and 3 kg weight loss. Physical examination revealed restricted active shoulder mobility. Magnetic resonance imaging showed a massive septated lesion in the glenoid that infiltrated adjacent tissues, indicating sarcoma. Core needle biopsy revealed metastatic poorly differentiated squamous cell cancer. Positron emission tomography scan results showed a primary lung tumor (stage IVB) with metastases to the left adrenal gland and a large mass in the right glenoid. This case describes the first documented case of metastatic lung squamous cell carcinoma to the shoulder glenoid, an uncommon metastatic location.

OrthopedicsVol. 49(2)
American University of Beirut Medical Center (LB)
Good health and well-being
Openalex Percentile: Top 7%
Management of metastatic bone disease
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Pulmonary Squamous Cell Carcinoma Presenting as Glenoid Bone Metastasis: A Case Report — Mohamad Nassereddine, Saïd Saghieh, et al. · Orthopedics (2026) | TGRS Research Map | TGRS