First oral GLP-1 receptor agonist approved for weight loss

Oral semaglutide (Wegovy) is the first oral glucagon-like peptide-1 receptor agonist to be approved for weight loss. Warnings and adverse effects remain the same for oral semaglutide as for subcutaneous semaglutide. Nurses should teach patients how to take oral semaglutide daily to promote absorption of the drug and prevent drug interactions.

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Publication Details

Journal
AJN American Journal of Nursing
Published
2026-03-26
DOI
https://doi.org/10.1097/ajn.0000000000000276b
Primary Topic
Diabetes Treatment and Management
Type
article
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article

First oral GLP-1 receptor agonist approved for weight loss

Diane S. Aschenbrenner
AJN American Journal of Nursing
Diabetes Treatment and Management
article

First oral GLP-1 receptor agonist approved for weight loss

Diane S. Aschenbrenner
article en

Abstract

Oral semaglutide (Wegovy) is the first oral glucagon-like peptide-1 receptor agonist to be approved for weight loss. Warnings and adverse effects remain the same for oral semaglutide as for subcutaneous semaglutide. Nurses should teach patients how to take oral semaglutide daily to promote absorption of the drug and prevent drug interactions.

AJN American Journal of NursingVol. 126(4)
Johns Hopkins University (US), The Dialogue (US)
Openalex Percentile: Top 8%
Diabetes Treatment and Management
DOISourceOpenAlex
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First oral GLP-1 receptor agonist approved for weight loss — Diane S. Aschenbrenner · AJN American Journal of Nursing (2026) | TGRS Research Map | TGRS