Sex differences in chemotherapy-induced neuropathic pain: mechanisms and pharmacotherapy
Sex is a crucial biological variable in CIPN, influencing drug efficacy through sex-specific neuroimmune mechanisms and hormonal regulation. These findings underscore the necessity of incorporating sex as a key variable in analgesic development and clinical practice to achieve personalized pain management in CIPN patients.
Authors
- Yixin Liu
- Xinyi Wu
- Xin Chen (ORCID: https://orcid.org/0000-0003-3668-4830)
- Yu Chen (ORCID: https://orcid.org/0000-0002-3647-2056)
- Litao Chen
Institutions
- Ningbo University (CN)
- Ningbo Kangning Hospital (CN)
Publication Details
- Journal
- Journal of Pharmacy and Pharmacology
- Published
- 2026-03-01
- DOI
- https://doi.org/10.1093/jpp/rgag025
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00