Human skin responses to UV (predominantly UVC at 254 nm) irradiation – in vivo kinetics of morphological changes and recovery using non-invasive two-photon tomography

The results obtained in this in vivo study confirm that UV (predominantly UVC at 254 nm) has damaging effect on all skin layers. Two-photon tomography is an effective non-invasive method for in vivo imaging morphological changes in the skin following UV irradiation and for studying severe photodamage.

Authors

Publication Details

Journal
Skin Pharmacology and Physiology
Published
2026-03-26
DOI
https://doi.org/10.1159/000551755
Primary Topic
Skin Protection and Aging
Type
article
Field-Weighted Citation Impact
0.00
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article

Human skin responses to UV (predominantly UVC at 254 nm) irradiation – in vivo kinetics of morphological changes and recovery using non-invasive two-photon tomography

Tatiana B. Lepekhina, Maxim E. Darvin, David A. Lopez Guardado, Yury V. Kistenev et al.
Skin Pharmacology and Physiology
Skin Protection and Aging
article

Human skin responses to UV (predominantly UVC at 254 nm) irradiation – in vivo kinetics of morphological changes and recovery using non-invasive two-photon tomography

Tatiana B. Lepekhina, Maxim E. Darvin, David A. Lopez Guardado, Yury V. Kistenev, Viktor V. Nikolaev
article en

Abstract

The results obtained in this in vivo study confirm that UV (predominantly UVC at 254 nm) has damaging effect on all skin layers. Two-photon tomography is an effective non-invasive method for in vivo imaging morphological changes in the skin following UV irradiation and for studying severe photodamage.

Skin Pharmacology and Physiology
Good health and well-being
Openalex Percentile: Top 6%
Skin Protection and Aging
DOISourceOpenAlex
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Human skin responses to UV (predominantly UVC at 254 nm) irradiation – in vivo kinetics of morphological changes and recovery using non-invasive two-photon tomography — Tatiana B. Lepekhina, Maxim E. Darvin, et al. · Skin Pharmacology and Physiology (2026) | TGRS Research Map | TGRS