Transcriptomic Analysis of Adipose-Derived Stem Cell Therapy Modulating B Cell Immune Tolerance in Vascularized Composite Allotransplantation
ADSC-based therapy combined with short-term immunosuppression promotes immune tolerance in VCA by modulating B cell-related gene expression. These findings suggest that targeting B cell-mediated pathways may provide a novel approach may offer a novel therapeutic strategy for clinical application in VCA.
Authors
- Rong‐Fu Chen (ORCID: https://orcid.org/0000-0001-7529-5390)
- Chia-Chun Lee (ORCID: https://orcid.org/0000-0003-2342-0553)
- Keng-Fan Liu
- Yun-Ting Li
- Yur-Ren Kuo
- Wei Yu Chen
Institutions
- National Sun Yat-sen University (TW)
- Kaohsiung Medical University (TW)
- Duke-NUS Medical School (SG)
Publication Details
- Journal
- Plastic & Reconstructive Surgery
- Published
- 2026-03-26
- DOI
- https://doi.org/10.1097/prs.0000000000013074
- Primary Topic
- Organ and Tissue Transplantation Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00