Impact of COVID-19 vaccination on radiation-induced lung injury in breast cancer patients: a retrospective cohort study

The findings of this study indicate that the administration of the COVID-19 vaccine prior to the commencement of radiation therapy is not associated with an increased likelihood of pulmonary toxicity. Although a slight protective effect was observed with two vaccine doses, it was not statistically significant. The retrospective nature of the study and the limited sample size necessitate the execution of larger, prospective, long-term follow-up studies to elucidate the underlying immunological mechanisms.