European Standard Clinical Practice Recommendations for Cutaneous Melanoma in Children and Adolescents
Cutaneous melanoma in children and adolescents is an extremely rare malignancy that poses significant diagnostic and therapeutic challenges due to limited clinical evidence and a lack of specific treatment guidelines. This document, developed by the European Cooperative Study Group for Pediatric Rare Tumors (EXPeRT), updates and systematizes previous recommendations by integrating recent advances. It particularly emphasizes the need for accurate diagnosis through expert pathology review, multidisciplinary discussion, appropriate surgical management, and the important role of systemic treatments now available, also in pediatric age. A strengthened collaboration with adult oncologists is fundamental to optimizing strategies and improving outcomes.
Authors
- Alice Indini (ORCID: https://orcid.org/0000-0001-8686-4106)
- Yves Réguerre (ORCID: https://orcid.org/0000-0001-7192-046X)
- Michaela Kuhlen (ORCID: https://orcid.org/0000-0003-4577-0503)
- Luca Bergamaschi (ORCID: https://orcid.org/0000-0003-2149-329X)
- J. Chanal (ORCID: https://orcid.org/0000-0002-8699-6755)
- S. Fraitag
- Ricardo López Almaraz (ORCID: https://orcid.org/0000-0001-5521-9892)
- Ewa Bień (ORCID: https://orcid.org/0000-0002-2091-2686)
- Małgorzata Krawczyk (ORCID: https://orcid.org/0000-0001-7093-8975)
- Michael Abele (ORCID: https://orcid.org/0000-0002-9780-603X)
- Alfonso Berrocal Jaime
- Ines B. Brecht
- Andrea Ferrari
- Thomas K. Eigentler
- Stefano Chiaravalli
- Daniel Orbach
Institutions
- Hôpital Necker-Enfants Malades (FR)
- University of Augsburg (DE)
- University of Milan (IT)
- Université Paris Sciences et Lettres (FR)
- Centre Hospitalier Universitaire de La Réunion (RE)
- BioCruces Health research Institute (ES)
- Assistance Publique – Hôpitaux de Paris (FR)
- University Children's Hospital Tübingen (DE)
- Hospital General Universitario De Valencia (ES)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
- Expression Génétique Microbienne (FR)
- Gdańsk Medical University (PL)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2026-03-26
- DOI
- https://doi.org/10.1002/1545-5017.70244
- Primary Topic
- Cutaneous Melanoma Detection and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00