Staying on track: collagen fibers orientation strongly affects thrombi formation at high shear
Type III lengthwise collagen fibers are the ones promoting platelet translocation and stable adhesion at high shear rates, which may be relevant for triggering thrombus formation in vivo.
Authors
- P. Mangin
- Е.А. Melnikova (ORCID: https://orcid.org/0000-0002-4253-2182)
- Mikhail A Panteleev
- Dmitry Yu. Nechipurenko
Institutions
- Center for Theoretical Problems of Physicochemical Pharmacology (RU)
- Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology (RU)
- Université de Strasbourg (FR)
Publication Details
- Journal
- Thrombosis and Haemostasis
- Published
- 2026-03-26
- DOI
- https://doi.org/10.1055/a-2841-9953
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00