Angiotensin‐(1–7) Alleviates Isoproterenol‐Induced Cardiac Hypertrophy by Suppressing Autophagy and Apoptosis Through the Synergistic Action of Mas Receptor and Angiotensin <scp>II</scp> Type 2 Receptor
Ang-(1-7) ameliorates ISO-induced cardiac hypertrophy by suppressing excessive autophagy and apoptosis via synergistic MasR-AT<sub>2</sub>R signaling. Receptor crosstalk may represent a therapeutic entry point for pathological hypertrophy.
Authors
- Lan Hong (ORCID: https://orcid.org/0000-0003-1010-6039)
- Xin Wang (ORCID: https://orcid.org/0000-0002-7296-9406)
- Honghua Jin
- Yu Guo
- Fei Guo
- Siyao Fan
Institutions
- Yanbian University (CN)
- Yanbian University Hospital (CN)
Publication Details
- Journal
- Acta Physiologica
- Published
- 2026-03-26
- DOI
- https://doi.org/10.1111/apha.70200
- Primary Topic
- Renin-Angiotensin System Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00