Severe agranulocytosis in patient with Graves’ disease on second exposure to carbimazole

Antithyroid drugs (ATDs) are rarely associated with agranulocytosis. ATD-induced agranulocytosis is regarded as a serious life-threatening emergency. The only option for the management of patients with Graves' disease-developed agranulocytosis is surgery. Educating the patients regarding the symptoms of agranulocytosis is vital for saving their life. ATD-induced agranulocytosis can happen long time after exposure or even after second exposure to these drugs.

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Publication Details

Journal
Endocrinology Diabetes and Metabolism Case Reports
Published
2026-01-01
DOI
https://doi.org/10.1530/edm-25-0131
Primary Topic
Blood disorders and treatments
Type
article
Field-Weighted Citation Impact
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article

Severe agranulocytosis in patient with Graves’ disease on second exposure to carbimazole

Hady Gad, Wael Elsaify, Ahmed M. Hanafy, Ammar W. Ashor et al.
Endocrinology Diabetes and Metabolism Case Reports
Blood disorders and treatments
article

Severe agranulocytosis in patient with Graves’ disease on second exposure to carbimazole

Hady Gad, Wael Elsaify, Ahmed M. Hanafy, Ammar W. Ashor, Simon Ashwell, Waqar Ahmad, Barkavi Dhakshinamoorthy
article en

Abstract

Antithyroid drugs (ATDs) are rarely associated with agranulocytosis. ATD-induced agranulocytosis is regarded as a serious life-threatening emergency. The only option for the management of patients with Graves' disease-developed agranulocytosis is surgery. Educating the patients regarding the symptoms of agranulocytosis is vital for saving their life. ATD-induced agranulocytosis can happen long time after exposure or even after second exposure to these drugs.

Endocrinology Diabetes and Metabolism Case ReportsVol. 2026(1)
Mustansiriyah University (IQ), South Tees Hospitals NHS Foundation Trust (GB)
Good health and well-being
Openalex Percentile: Top 7%
Blood disorders and treatments
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