Ultrarapid Lispro (Lyumjev) Has an Improved Pharmacokinetic Profile for Exercise Compared With Humalog, Resulting in Less Exercise-Associated Hypoglycemia in Adults With Type 1 Diabetes on Open-Loop Continuous Subcutaneous Insulin Infusion

Using Lyumjev in conventional CSII pump therapy provides more effective BRRs prior to exercise compared with Humalog, with fewer hypoglycemic events in active adults with type 1 diabetes.

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Publication Details

Journal
Diabetes Care
Published
2026-03-26
DOI
https://doi.org/10.2337/dc25-2294
Primary Topic
Diabetes Management and Research
Type
article
Field-Weighted Citation Impact
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article

Ultrarapid Lispro (Lyumjev) Has an Improved Pharmacokinetic Profile for Exercise Compared With Humalog, Resulting in Less Exercise-Associated Hypoglycemia in Adults With Type 1 Diabetes on Open-Loop Continuous Subcutaneous Insulin Infusion

Alexander Abitbol, Elizabeth LaBell, Jennifer Leohr, David E. Coutant et al.
Diabetes Care
Diabetes Management and Research
article

Ultrarapid Lispro (Lyumjev) Has an Improved Pharmacokinetic Profile for Exercise Compared With Humalog, Resulting in Less Exercise-Associated Hypoglycemia in Adults With Type 1 Diabetes on Open-Loop Continuous Subcutaneous Insulin Infusion

Alexander Abitbol, Elizabeth LaBell, Jennifer Leohr, David E. Coutant, ARITRA GHOSH, Michael C. Riddell, Lauren V. Turner
article en

Abstract

Using Lyumjev in conventional CSII pump therapy provides more effective BRRs prior to exercise compared with Humalog, with fewer hypoglycemic events in active adults with type 1 diabetes.

Diabetes Care
Eli Lilly (United States) (US), York University (CA), LMC Diabetes & Endocrinology (Canada) (CA)
Zero hunger
Openalex Percentile: Top 8%
Diabetes Management and Research
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