Platelet‐Activating Factor Pathway in Women With Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity
The PAF-PAFR axis is upregulated in obesity-associated MASLD and is strongly linked to inflammatory and injury-related histological features, supporting PAFR as a potential therapeutic target. Conversely, plasma Lp-PLA2 does not appear to be a reliable noninvasive biomarker of MASLD severity in women with obesity.
Authors
- Javier Camaron
- Carmen Aguilar (ORCID: https://orcid.org/0000-0002-4440-562X)
- Margarita Vives (ORCID: https://orcid.org/0000-0001-6537-1476)
- David Riesco (ORCID: https://orcid.org/0000-0001-7188-7188)
- Razieh Mahmoudian
- Helena Clavero‐Mestres
- Fátima Sabench
- Teresa Auguet
- Joan Duran‐Bertran
- Salomé Martínez
- Sara Muñiz‐Piera
- Marta París
Institutions
- Institut de Recerca Biomèdica Catalunya Sud (ES)
- Hospital Universitari Joan XXIII de Tarragona (ES)
Publication Details
- Journal
- Obesity
- Published
- 2026-03-26
- DOI
- https://doi.org/10.1002/oby.70178
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00