Development and Validation of a Parsimonious Risk Stratification Model for Pancreatic Cancer
In this validation cohort study, PRIME was a transparent EHR-based model that effectively stratified PDAC risk across diverse US health systems and generalized internationally. Prospective studies should evaluate for EHR-guided PDAC case-finding and integration with blood-based early-detection assays.
Authors
- Emil Agarunov
- Morgan E. Grams (ORCID: https://orcid.org/0000-0002-4430-6023)
- Lucas A. Mavromatis (ORCID: https://orcid.org/0000-0003-2921-4654)
- Viktor Zlatanic
- Michael D. Kluger (ORCID: https://orcid.org/0000-0003-4311-078X)
- Narges Razavian (ORCID: https://orcid.org/0000-0002-9922-6370)
- Shenin A. Sanoba
- Leora I. Horwitz (ORCID: https://orcid.org/0000-0003-1800-6040)
- Tamas A. Gonda
- Anirban Maitra
Institutions
- New York University (US)
Publication Details
- Journal
- JAMA Oncology
- Published
- 2026-03-26
- DOI
- https://doi.org/10.1001/jamaoncol.2026.0372
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00