Cryptoxanthin as a multitarget neuroprotective agent: mechanistic and in silico perspectives
The findings of this review highlight β-cryptoxanthin as a promising candidate for future neurotherapeutic investigation due to its multi-targeted mechanisms of action against key pathways implicated in neurodegeneration. Molecular docking results support its potential mechanistic role in modulating inflammation- and oxidative stress-related targets. However, these findings represent mechanistic plausibility rather than confirmed clinical efficacy, and further validation through preclinical and clinical studies is required.
Authors
- Ankit Awasthi (ORCID: https://orcid.org/0000-0002-3266-7649)
- Somdutt Mujwar (ORCID: https://orcid.org/0000-0003-4037-5475)
- Abhishek Chauhan
- Mohit Kumar (ORCID: https://orcid.org/0000-0003-0305-7427)
- Takveer Singh (ORCID: https://orcid.org/0000-0003-2979-1590)
- Arjun Sadhukhan
Institutions
- Chitkara University (IN)
Publication Details
- Journal
- Journal of Pharmacy and Pharmacology
- Published
- 2026-03-01
- DOI
- https://doi.org/10.1093/jpp/rgag029
- Primary Topic
- Antioxidant Activity and Oxidative Stress
- Type
- article
- Field-Weighted Citation Impact
- 0.00