Cryptoxanthin as a multitarget neuroprotective agent: mechanistic and in silico perspectives

The findings of this review highlight β-cryptoxanthin as a promising candidate for future neurotherapeutic investigation due to its multi-targeted mechanisms of action against key pathways implicated in neurodegeneration. Molecular docking results support its potential mechanistic role in modulating inflammation- and oxidative stress-related targets. However, these findings represent mechanistic plausibility rather than confirmed clinical efficacy, and further validation through preclinical and clinical studies is required.

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Publication Details

Journal
Journal of Pharmacy and Pharmacology
Published
2026-03-01
DOI
https://doi.org/10.1093/jpp/rgag029
Primary Topic
Antioxidant Activity and Oxidative Stress
Type
article
Field-Weighted Citation Impact
0.00
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article

Cryptoxanthin as a multitarget neuroprotective agent: mechanistic and in silico perspectives

Ankit Awasthi, Somdutt Mujwar, Abhishek Chauhan, Mohit Kumar et al.
Journal of Pharmacy and Pharmacology
Antioxidant Activity and Oxidative Stress
article

Cryptoxanthin as a multitarget neuroprotective agent: mechanistic and in silico perspectives

Ankit Awasthi, Somdutt Mujwar, Abhishek Chauhan, Mohit Kumar, Takveer Singh, Arjun Sadhukhan
article en

Abstract

The findings of this review highlight β-cryptoxanthin as a promising candidate for future neurotherapeutic investigation due to its multi-targeted mechanisms of action against key pathways implicated in neurodegeneration. Molecular docking results support its potential mechanistic role in modulating inflammation- and oxidative stress-related targets. However, these findings represent mechanistic plausibility rather than confirmed clinical efficacy, and further validation through preclinical and clinical studies is required.

Journal of Pharmacy and PharmacologyVol. 78(3)
Chitkara University (IN)
Openalex Percentile: Top 8%
Antioxidant Activity and Oxidative Stress
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Cryptoxanthin as a multitarget neuroprotective agent: mechanistic and in silico perspectives — Ankit Awasthi, Somdutt Mujwar, et al. · Journal of Pharmacy and Pharmacology (2026) | TGRS Research Map | TGRS