Local therapeutic strategies for neurocutaneous dysesthesia: from capsaicin to cannabinoids

Local therapy offers a valuable and often well-tolerated first step in managing ND. Unfortunately, high-quality evidence is scarce and treatment efficacy remains unpredictable. Clinicians are advised to start with low concentrations, discuss off-label use, and monitor for side effects. Until robust guidelines are available, a cautious trial-and-error approach remains the cornerstone of management.

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Publication Details

Journal
Journal of Dermatological Treatment
Published
2026-03-26
DOI
https://doi.org/10.1080/09546634.2026.2646556
Primary Topic
Anesthesia and Pain Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Local therapeutic strategies for neurocutaneous dysesthesia: from capsaicin to cannabinoids

Jade G. M. Logger, Jan Willem Kallewaard, Robbert Visscher, Patrick Kemperman
Journal of Dermatological Treatment
Anesthesia and Pain Management
article

Local therapeutic strategies for neurocutaneous dysesthesia: from capsaicin to cannabinoids

Jade G. M. Logger, Jan Willem Kallewaard, Robbert Visscher, Patrick Kemperman
article en

Abstract

Local therapy offers a valuable and often well-tolerated first step in managing ND. Unfortunately, high-quality evidence is scarce and treatment efficacy remains unpredictable. Clinicians are advised to start with low concentrations, discuss off-label use, and monitor for side effects. Until robust guidelines are available, a cautious trial-and-error approach remains the cornerstone of management.

Journal of Dermatological TreatmentVol. 37(1)
Maastricht University Medical Centre (NL), Maastricht University (NL), Zorggroep Meander (NL), Amsterdam Neuroscience (NL), Amsterdam University Medical Centers (NL), Rijnstate Hospital (NL), University of Amsterdam (NL)
Good health and well-being
Openalex Percentile: Top 7%
Anesthesia and Pain Management
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