Impact of 5‐ASA discontinuation in children with ulcerative colitis on biologic therapy: A propensity score‐matched study

5-ASA discontinuation might negatively impact the clinical course of children with UC treated with anti-TNF. Considering the good safety profile of the drug, continuing mesalamine can be suggested as a prudent approach.

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Publication Details

Journal
Journal of Pediatric Gastroenterology and Nutrition
Published
2026-03-26
DOI
https://doi.org/10.1002/jpn3.70415
Primary Topic
Inflammatory Bowel Disease
Type
article
Field-Weighted Citation Impact
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article

Impact of 5‐ASA discontinuation in children with ulcerative colitis on biologic therapy: A propensity score‐matched study

Mara Corpino, Maria Teresa Fioretti, Giulia Mancuso, Luca Scarallo et al.
Journal of Pediatric Gastroenterology and Nutrition
Inflammatory Bowel Disease
article

Impact of 5‐ASA discontinuation in children with ulcerative colitis on biologic therapy: A propensity score‐matched study

Mara Corpino, Maria Teresa Fioretti, Giulia Mancuso, Luca Scarallo, Maria Teresa Illiceto, L. Norsa, Serena Arrigo, Giovanna Zuin, Giulia D'Arcangelo, Matteo Bramuzzo, Marina Aloi, Claudio Romano, Paolo Lionetti
article en

Abstract

5-ASA discontinuation might negatively impact the clinical course of children with UC treated with anti-TNF. Considering the good safety profile of the drug, continuing mesalamine can be suggested as a prudent approach.

Journal of Pediatric Gastroenterology and Nutrition
University of Messina (IT), University of Milan (IT), IRCCS Materno Infantile Burlo Garofolo (IT), Istituto Giannina Gaslini (IT), Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT), Ospedale Papa Giovanni XXIII (IT), Ospedale di Santo Spirito (IT), Azienda Ospedaliera San Gerardo (IT), Meyer Children's Hospital (IT), Federico II University Hospital (IT), Ospedale Microcitemico (IT), Ospedale dei Bambini Vittore Buzzi (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), University of Naples Federico II (IT), Sapienza University of Rome (IT)
Good health and well-being
Openalex Percentile: Top 7%
Inflammatory Bowel Disease
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Impact of 5‐ASA discontinuation in children with ulcerative colitis on biologic therapy: A propensity score‐matched study — Mara Corpino, Maria Teresa Fioretti, et al. · Journal of Pediatric Gastroenterology and Nutrition (2026) | TGRS Research Map | TGRS