Integrative Analysis Identifies Lactylation-Associated Hub Genes in Septic Cardiomyopathy
This study, through integrated bioinformatics and initial experimental validation, identifies GADD45B, STAT3, and SLC7A5 as central hub genes in SCM and proposes their potential regulation by lactylation as a novel hypothesis for future mechanistic investigation.
Authors
- Wei Xiong (ORCID: https://orcid.org/0000-0002-2532-2503)
- YiTing Chen
- Jinwei Dai (ORCID: https://orcid.org/0009-0003-5983-1757)
- Rui Jin
- Zhaoxin Qian
- Xiaolei Zhang
Institutions
- Central South University (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- Shock
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1097/shk.0000000000002819
- Primary Topic
- Cardiac Fibrosis and Remodeling
- Type
- article
- Field-Weighted Citation Impact
- 0.00