Fibrin-Heparin-Coated Intracranial Stents as Salvage Therapy in Pediatric Focal Cerebral Arteriopathy of Inflammatory Type
Arterial ischemic stroke (AIS) in children is frequently associated with underlying arteriopathy. We report a 13-year-old male with progressive AIS due to focal cerebral arteriopathy of inflammatory type (FCA-i). Despite initial medical therapy-including antiplatelet agents, immunosuppressive therapy, antimicrobial treatment, and intra-arterial spasmolysis-he experienced clinical and radiographic deterioration. Endovascular therapy with balloon angioplasty and fibrin-heparin-coated intracranial stents achieved successful revascularization and stabilization. Vessel wall MRI and elevated <i>Mycoplasma pneumoniae</i> antibodies supported the diagnosis of FCA-i. Follow-up demonstrated sustained stent patency and vascular improvement, with persistent distal upper-extremity-predominant hemiparesis.
Authors
- Christian Brickmann (ORCID: https://orcid.org/0000-0001-9085-4242)
- Marija Čagalj
- Thomas Witton-Davies
- Maximilian Koppers
- Anastasios Mpotsaris
- Anna Schaper
Institutions
- München Klinik (DE)
Publication Details
- Journal
- American Journal of Neuroradiology
- Published
- 2026-03-26
- DOI
- https://doi.org/10.3174/ajnr.a9317
- Primary Topic
- Intracranial Aneurysms: Treatment and Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00