Cracking the nut of <i>NUTM1</i> rearrangements in infant leukemia

In this issue of Blood, Nishimura et al 1 demonstrate that expression of NUTM1 fusion genes in hematopoietic progenitors can induce a "one-hit leukemia" by driving differentiation to highly proliferating, stem-like B-cell progenitors.

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Publication Details

Journal
Blood
Published
2026-03-26
DOI
https://doi.org/10.1182/blood.2025032530
Primary Topic
Protein Degradation and Inhibitors
Type
article
Field-Weighted Citation Impact
0.00
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article

Cracking the nut of NUTM1 rearrangements in infant leukemia

Ruth Shiloh, S. Izraeli
Blood
Protein Degradation and Inhibitors
article

Cracking the nut of NUTM1 rearrangements in infant leukemia

Ruth Shiloh, S. Izraeli
article en

Abstract

In this issue of Blood, Nishimura et al 1 demonstrate that expression of NUTM1 fusion genes in hematopoietic progenitors can induce a "one-hit leukemia" by driving differentiation to highly proliferating, stem-like B-cell progenitors.

BloodVol. 147(13)
Tel Aviv University (IL), Schneider Children's Medical Center (IL), Schneider Children's Hospital (US)
Zero hunger
Openalex Percentile: Top 8%
Protein Degradation and Inhibitors
DOIOpen Access PDFOpenAlex
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Cracking the nut of <i>NUTM1</i> rearrangements in infant leukemia — Ruth Shiloh, S. Izraeli · Blood (2026) | TGRS Research Map | TGRS