A smart P-gp inhibitor-drug conjugate nanomedicine overcomes administration challenges and multidrug resistance in breast cancer therapy

Docetaxel (DTX), a first-line taxane chemotherapeutic agent, is widely used in the treatment of breast cancer. However, its clinical efficacy is often limited by multidrug resistance (MDR), primarily driven by...

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Publication Details

Journal
Biomaterials Science
Published
2026-01-01
DOI
https://doi.org/10.1039/d6bm00280c
Primary Topic
Drug Transport and Resistance Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

A smart P-gp inhibitor-drug conjugate nanomedicine overcomes administration challenges and multidrug resistance in breast cancer therapy

Yingchun Liu, Wenhui Gao, Penghui Wang, Deyue Yan et al.
Biomaterials Science
Drug Transport and Resistance Mechanisms
article

A smart P-gp inhibitor-drug conjugate nanomedicine overcomes administration challenges and multidrug resistance in breast cancer therapy

Yingchun Liu, Wenhui Gao, Penghui Wang, Deyue Yan, Yao Wang, Wei Hsiang Huang, Xuelin Xia
article en

Abstract

Docetaxel (DTX), a first-line taxane chemotherapeutic agent, is widely used in the treatment of breast cancer. However, its clinical efficacy is often limited by multidrug resistance (MDR), primarily driven by...

Biomaterials Science
Good health and well-being
Openalex Percentile: Top 8%
Drug Transport and Resistance Mechanisms
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A smart P-gp inhibitor-drug conjugate nanomedicine overcomes administration challenges and multidrug resistance in breast cancer therapy — Yingchun Liu, Wenhui Gao, et al. · Biomaterials Science (2026) | TGRS Research Map | TGRS