Wnt5a‐Induced Exosomes From Bone Marrow Mesenchymal Stem Cells Promote Spinal Cord Injury Repair by Modulating Immune Cell Phenotypes and Alleviating Neuroinflammation via the <scp>NF</scp> ‐ <scp>κB</scp> Pathway
Collectively, these findings indicate that Wnt5a enhances the neuroregenerative potential of BMSC-Exos by modulating immune responses and suppressing neuroinflammation, likely through inhibiting the NF-κB signaling pathway.
Authors
- Dongliang Lin (ORCID: https://orcid.org/0000-0001-7149-7243)
- Da Luo (ORCID: https://orcid.org/0000-0003-1183-8354)
- Binshan Zhang (ORCID: https://orcid.org/0000-0003-2484-7639)
- Yuting Wu
- Enhui Feng
- Ling Chen (ORCID: https://orcid.org/0000-0001-6074-523X)
- Da Guo (ORCID: https://orcid.org/0009-0006-8978-1115)
- Zhifeng Hu
- Xing Li
- Chaoyi Yin
- Sheng Luo
- Ke Ni
- Chaolun Liang
- Lin Ma
Institutions
- Dalian Ocean University (CN)
- Guangzhou University of Chinese Medicine (CN)
- State Administration of Traditional Chinese Medicine of the People's Republic of China (CN)
- Dongguan University of Technology (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Dongguan People’s Hospital (CN)
- Zhongshan Hospital (CN)
- Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2026-03-26
- DOI
- https://doi.org/10.1002/cns.70834
- Primary Topic
- Spinal Cord Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00