<i>German Million Children Cohort</i> : a historical birth cohort based on claims data to investigate the impact of immunisation and other early life factors on the risk of cancer and other diseases in childhood – cohort profile

While our first study with this historical cohort is dedicated to the question of whether immunity to childhood infections that are covered by the recommended baseline vaccination scheme reduces the risk of childhood cancer, the cohort will offer further opportunities. This includes the evaluation of additional factors potentially influencing the risk of cancer and other diseases in childhood, as well as an extension of the inclusion period beyond 2018 to also include children born during the COVID-19 pandemic.

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Publication Details

Journal
BMJ Open
Published
2026-03-01
DOI
https://doi.org/10.1136/bmjopen-2025-113411
Primary Topic
Acute Lymphoblastic Leukemia research
Type
article
Field-Weighted Citation Impact
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article

German Million Children Cohort : a historical birth cohort based on claims data to investigate the impact of immunisation and other early life factors on the risk of cancer and other diseases in childhood – cohort profile

U Haug, Rajini Nagrani, Bianca Kollhorst, Manuela Marron et al.
BMJ Open
Acute Lymphoblastic Leukemia research
article

German Million Children Cohort : a historical birth cohort based on claims data to investigate the impact of immunisation and other early life factors on the risk of cancer and other diseases in childhood – cohort profile

U Haug, Rajini Nagrani, Bianca Kollhorst, Manuela Marron, Lara Kim Brackmann, Loviisa Mulanje, Wolfgang Ahrens, Sophie Langbein
article en

Abstract

While our first study with this historical cohort is dedicated to the question of whether immunity to childhood infections that are covered by the recommended baseline vaccination scheme reduces the risk of childhood cancer, the cohort will offer further opportunities. This includes the evaluation of additional factors potentially influencing the risk of cancer and other diseases in childhood, as well as an extension of the inclusion period beyond 2018 to also include children born during the COVID-19 pandemic.

BMJ OpenVol. 16(3)
University of Bremen (DE), Leibniz Institute for Prevention Research and Epidemiology - BIPS (DE)
Openalex Percentile: Top 10%
Acute Lymphoblastic Leukemia research
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