Novel zerumbone-amide-triazole hybrids as potential NF-κB pathway inhibitors: design, synthesis, cytotoxicity evaluation, computational studies, and mechanistic insights
A series of fifteen novel zerumbone-amide-triazole hybrids 12a-i and 15a-f were successfully designed and synthesized from azazerumbone II (2) via Click reaction. The cytotoxicity of these derivatives was evaluated against...
Authors
- Vu Tuan Kien
- Cao Thanh Hải (ORCID: https://orcid.org/0000-0003-0715-1517)
- Thanh Phuong Phan
- Khiếu Thị Tâm (ORCID: https://orcid.org/0000-0001-9942-3211)
- Loan Thi Thuy Le
- Thi Tham. Pham
- Chinh The Pham
- Truong Xuan Vuong
- Le Thi Lien
- T. T. Thao
- Nhung Thi Dao
- Lien Thi Vu
Publication Details
- Journal
- RSC Medicinal Chemistry
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1039/d6md00148c
- Primary Topic
- Ginger and Zingiberaceae research
- Type
- article
- Field-Weighted Citation Impact
- 0.00