Silver catalysed asymmetric [3+2] cycloaddition for the construction of 5−5-membered 1,3'-indolyl pyrrole atropisomers
An atropoenantioselective Ag-catalysed [3+2] cycloaddition of N-alkynyl ketones with isocyanides has been developed to access 5−5-membered 1,3'-indolyl pyrroles bearing C-N axial chirality in high yields and excellent enantioselectivities. The resulting...
Authors
- Jinzhong Yao (ORCID: https://orcid.org/0000-0003-2444-7731)
- Yan Xie (ORCID: https://orcid.org/0000-0003-3608-8887)
- Weihui Zhong
- Zhengguo Deng
- Jiayang Lv
- Fei Ling
- Xinyu Chen
- Chao Xiong
Publication Details
- Journal
- Chemical Communications
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1039/d6cc00517a
- Primary Topic
- Axial and Atropisomeric Chirality Synthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00