Nerve Ultrasound Detects Peripheral Nerve Enlargement in Cerebrotendinous Xanthomatosis
This study demonstrates that nerve ultrasound can detect peripheral nerve enlargement in CTX, even in preclinical stages of polyneuropathy. Enlargement of peripheral nerves may be a sensitive marker of disease severity and peripheral nerve involvement. The role of nerve ultrasound as a diagnostic tool in CTX is promising, and future longitudinal studies are needed to determine its value in disease monitoring.
Authors
- Paulo Ribeiro Nóbrega (ORCID: https://orcid.org/0000-0002-0021-9358)
- Rodrigo Fagundes da Rosa (ORCID: https://orcid.org/0009-0007-6664-9012)
- Pedro Lucas G. S. B. Lima
- Antonio Edvan Camelo‐Filho
- Ana Lucila Moreira
- André L. S. Pessoa
- Tito B. S. Soares
- Pedro Braga‐Neto
- Luis Edmundo T. A. Furtado
Institutions
- Universidade Estadual do Ceará (BR)
- Universidade de São Paulo (BR)
- Universidade Federal do Ceará (BR)
- Centro Universitário Una (BR)
- Hospital Infantil Albert Sabin (BR)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
Publication Details
- Journal
- Muscle & Nerve
- Published
- 2026-03-26
- DOI
- https://doi.org/10.1002/mus.70221
- Primary Topic
- Cholesterol and Lipid Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00