Comparative and Complementary Diagnostic Value of Dermatoscopy and Clinical Close-up Photography in Skin Cancer Diagnosis: A Study from the MILK10k Dataset

Dermatoscopy alone yields higher sensitivity for malignant lesions but lower specificity for nevi than clinical close-up images. The latter provides complementary diagnostic cues, underscoring the value of integrating both modalities for optimal assessment.

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Publication Details

Journal
Journal of the American Academy of Dermatology
Published
2026-03-01
DOI
https://doi.org/10.1016/j.jaad.2026.03.069
Primary Topic
Cutaneous Melanoma Detection and Management
Type
article
Field-Weighted Citation Impact
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article

Comparative and Complementary Diagnostic Value of Dermatoscopy and Clinical Close-up Photography in Skin Cancer Diagnosis: A Study from the MILK10k Dataset

Konstantinos Liopyris, CJ Longo, Zoé Apalla, Anna K. Wolber et al.
Journal of the American Academy of Dermatology
Cutaneous Melanoma Detection and Management
article

Comparative and Complementary Diagnostic Value of Dermatoscopy and Clinical Close-up Photography in Skin Cancer Diagnosis: A Study from the MILK10k Dataset

Konstantinos Liopyris, CJ Longo, Zoé Apalla, Anna K. Wolber, Cliff Rosendahl, Ofer Reiter, H. Peter Soyer, Aimilios Lallas, Philipp Tschandl, Ana Maria Forsea, Giuseppe Argenziano, Christoph Müller, Bengu Nisa Akay, Josep Malvehy, Iris Zalaudek, Susana Puig, Ashfaq Marghoob, Harald Kittler
article en

Abstract

Dermatoscopy alone yields higher sensitivity for malignant lesions but lower specificity for nevi than clinical close-up images. The latter provides complementary diagnostic cues, underscoring the value of integrating both modalities for optimal assessment.

Journal of the American Academy of Dermatology
University of Modena and Reggio Emilia (IT), Memorial Sloan Kettering Cancer Center (US), University of Trieste (IT), Ankara University (TR), Austrian Research Institute for Artificial Intelligence (AT), Carol Davila University of Medicine and Pharmacy (RO), Tel Aviv University (IL), University of Campania "Luigi Vanvitelli" (IT), Aristotle University of Thessaloniki (GR), Rabin Medical Center (IL), Princess Alexandra Hospital (AU), Emergency University (US), Hospital Clínic de Barcelona (ES), Andreas Sygros Hospital (GR), Mayne Pharma (Australia) (AU), Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES), Instituto de Investigación de Enfermedades Raras (ES), Universitat de Barcelona (ES), Medical University of Vienna (AT)
Openalex Percentile: Top 8%
Cutaneous Melanoma Detection and Management
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