Protective effects and mechanisms of <i>Panax notoginseng saponins</i> against gp120-induced cognitive impairment: a network pharmacology and metabolomics study
PNS confers neuroprotection against gp120-induced cognitive impairment by modulating the NOD-like receptor signaling pathway, which suppresses neuroinflammation and inhibits apoptosis.
Authors
- Siyu Xia
- Qiulan Chen (ORCID: https://orcid.org/0000-0001-6711-2304)
- Shanshan Li (ORCID: https://orcid.org/0000-0002-9021-8470)
- Danni Zhang (ORCID: https://orcid.org/0000-0001-7889-5746)
- Y F Zhou
- Mingyu Huang
- Xiyong Xiang
- Feizhang Qin
Institutions
- Guangxi Medical University (CN)
- Yulin Normal University (CN)
Publication Details
- Journal
- Journal of Pharmacy and Pharmacology
- Published
- 2026-03-01
- DOI
- https://doi.org/10.1093/jpp/rgag026
- Primary Topic
- Ginseng Biological Effects and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00