The use of intact fish skin grafts in the treatment of acute complicated bite wounds: a case report

Abstract The management of complex bite wounds, particularly in patients with comorbidities, presents a significant clinical challenge due to the high risk of infection and prolonged healing times. This case report highlights the successful use of intact fish skin grafts as a novel treatment modality for a primary contaminated bite wound at the patient with comorbidities such as diabetes mellitus and rheumatoid artritis with cortisone use. A 54-year-old European female patient with a medical history of rheumatoid arthritis and type 2 diabetes mellitus presented with a large, full-thickness dog bite wound on her right lower leg. Surgical debridement and broad-spectrum antibiotic administration, an intact Kerecis fish skin graft was applied and secured. The application of an intact fish skin xenograft, combined with surgical debridement and appropriate antibiotic therapy, proved to be a highly effective treatment for a complex bite wound in an immunocompromised patient.

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Publication Details

Journal
Journal of Surgical Case Reports
Published
2026-03-01
DOI
https://doi.org/10.1093/jscr/rjag197
Primary Topic
Marine Invertebrate Physiology and Ecology
Type
article
Field-Weighted Citation Impact
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article

The use of intact fish skin grafts in the treatment of acute complicated bite wounds: a case report

Thibika Sivakumar, Kostas Michael, Lukas Krähenbühl, Hans-Dieter Mäder et al.
Journal of Surgical Case Reports
Marine Invertebrate Physiology and Ecology
article

The use of intact fish skin grafts in the treatment of acute complicated bite wounds: a case report

Thibika Sivakumar, Kostas Michael, Lukas Krähenbühl, Hans-Dieter Mäder, Alexander Golowan, Jörg Lucian, Ivan Adamovic
article en

Abstract

Abstract The management of complex bite wounds, particularly in patients with comorbidities, presents a significant clinical challenge due to the high risk of infection and prolonged healing times. This case report highlights the successful use of intact fish skin grafts as a novel treatment modality for a primary contaminated bite wound at the patient with comorbidities such as diabetes mellitus and rheumatoid artritis with cortisone use. A 54-year-old European female patient with a medical history of rheumatoid arthritis and type 2 diabetes mellitus presented with a large, full-thickness dog bite wound on her right lower leg. Surgical debridement and broad-spectrum antibiotic administration, an intact Kerecis fish skin graft was applied and secured. The application of an intact fish skin xenograft, combined with surgical debridement and appropriate antibiotic therapy, proved to be a highly effective treatment for a complex bite wound in an immunocompromised patient.

Journal of Surgical Case ReportsVol. 2026(3)
Levanger Hospital (NO)
Life below water
Openalex Percentile: Top 4%
Marine Invertebrate Physiology and Ecology
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The use of intact fish skin grafts in the treatment of acute complicated bite wounds: a case report — Thibika Sivakumar, Kostas Michael, et al. · Journal of Surgical Case Reports (2026) | TGRS Research Map | TGRS