Association between pharmacological tenofovir adherence measures and subsequent 24-week viral load outcomes for people with HIV in South Africa

DBS TFV-DP was associated with viraemia at 24-weeks and could help predict future viraemia. Undetectable POC urine TFV was associated with recent ART initiation, current viraemia, and lower CD4 count.

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Publication Details

Journal
JAIDS Journal of Acquired Immune Deficiency Syndromes
Published
2026-03-26
DOI
https://doi.org/10.1097/qai.0000000000003866
Primary Topic
HIV-related health complications and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Association between pharmacological tenofovir adherence measures and subsequent 24-week viral load outcomes for people with HIV in South Africa

Yukteshwar Sookrajh, Monica Gandhi, Gail Hayward, Natasha Samsunder et al.
JAIDS Journal of Acquired Immune Deficiency Syndromes
HIV-related health complications and treatments
article

Association between pharmacological tenofovir adherence measures and subsequent 24-week viral load outcomes for people with HIV in South Africa

Yukteshwar Sookrajh, Monica Gandhi, Gail Hayward, Natasha Samsunder, Pravi Moodley, Philip J. Turner, Christopher Butler, Nicola Bodley, Katya Govender, Jienchi Dorward, Paul K. Drain, Nigel Garrett
article en

Abstract

DBS TFV-DP was associated with viraemia at 24-weeks and could help predict future viraemia. Undetectable POC urine TFV was associated with recent ART initiation, current viraemia, and lower CD4 count.

JAIDS Journal of Acquired Immune Deficiency Syndromes
National Health Laboratory Service (ZA), Desmond Tutu HIV Foundation (ZA), University of Cape Town (ZA), University of California, San Francisco (US), University of Washington (US), Centre for the AIDS Programme of Research in South Africa (ZA), eThekwini Municipality (ZA), University of Oxford (GB), Africa Health Research Institute (ZA), Centre for Sustainable Healthcare (GB), Seattle University (US), University of KwaZulu-Natal (ZA)
Good health and well-being
Openalex Percentile: Top 8%
HIV-related health complications and treatments
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Association between pharmacological tenofovir adherence measures and subsequent 24-week viral load outcomes for people with HIV in South Africa — Yukteshwar Sookrajh, Monica Gandhi, et al. · JAIDS Journal of Acquired Immune Deficiency Syndromes (2026) | TGRS Research Map | TGRS