Engineering Oxaliplatin(IV) Prodrugs with Monohaloacetates for Redox-Responsive and Multimodal Anticancer Activity
A series of novel oxaliplatin(IV) complexes bearing monohaloacetic acids (MAAs) was synthesised to address the limitations of platinum-based chemotherapy related to severe side effects and resistance phenomena. Both symmetrical [Pt(DACH)(ox)(MAA)₂]...
Authors
- Iogann Tolbatov (ORCID: https://orcid.org/0000-0001-9700-5331)
- Alessandro Pratesi (ORCID: https://orcid.org/0000-0002-9553-9943)
- Damiano Cirri (ORCID: https://orcid.org/0000-0001-9175-9562)
- Alessandro Marrone (ORCID: https://orcid.org/0000-0002-8311-8172)
- Chiara Gabbiani (ORCID: https://orcid.org/0000-0002-8468-4838)
- Paolo Paoli (ORCID: https://orcid.org/0000-0001-6448-7266)
- Francesca Binacchi (ORCID: https://orcid.org/0000-0002-9256-3665)
- Martina Porco
- Rebecca Sodano (ORCID: https://orcid.org/0009-0005-7819-1796)
- Tiziana Funaioli
Publication Details
- Journal
- Dalton Transactions
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1039/d6dt00471g
- Primary Topic
- Metal complexes synthesis and properties
- Type
- article
- Field-Weighted Citation Impact
- 0.00