Focal Fatty Change After Total Pancreatectomy Mimics Hypervascular Liver Tumor

Summary: Focal fatty change (FFC) can exhibit various patterns. Therefore, multifocal cases may require differentiation from metastatic liver tumors because the diagnosis is challenging in case of a history of treatment for malignant tumors. Herein, we report the case of a 65-year-old man with FFC who underwent total pancreatectomy for advanced intraductal papillary mucinous carcinoma. In this case, regular replacement of the percutaneous transhepatic cholangial drain was performed for postoperative anastomotic stenosis. The FFC showed a multifocal pattern with arterial-phase hyperenhancement and washout patterns; therefore, differentiation from not only metastatic liver tumors but also from hypervascular liver tumors including hepatocellular carcinoma was required. This case report highlights that although FFC can have a variety of imaging patterns; it can present arterial-phase hyperenhancement and washout patterns.

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Publication Details

Journal
The Kurume Medical Journal
Published
2026-01-01
DOI
https://doi.org/10.2739/kurumemedj.ms721-4007
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
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article

Focal Fatty Change After Total Pancreatectomy Mimics Hypervascular Liver Tumor

Koichi Higaki, Keiichi Mitsuyama, Hiroshi Kawano, S Shibata et al.
The Kurume Medical Journal
Pancreatic and Hepatic Oncology Research
article

Focal Fatty Change After Total Pancreatectomy Mimics Hypervascular Liver Tumor

Koichi Higaki, Keiichi Mitsuyama, Hiroshi Kawano, S Shibata, Takeshi Aoyagi, Hiromasa Watanabe, Osamu Tsuruta, Shusuke Okamura, Kohei Ota, YUSUKE AOKI, WATARU FUKAMI, ERINA UENO, YUSUKE NAKAMURA, TAKUMI KAWAGUCHI
article en

Abstract

Summary: Focal fatty change (FFC) can exhibit various patterns. Therefore, multifocal cases may require differentiation from metastatic liver tumors because the diagnosis is challenging in case of a history of treatment for malignant tumors. Herein, we report the case of a 65-year-old man with FFC who underwent total pancreatectomy for advanced intraductal papillary mucinous carcinoma. In this case, regular replacement of the percutaneous transhepatic cholangial drain was performed for postoperative anastomotic stenosis. The FFC showed a multifocal pattern with arterial-phase hyperenhancement and washout patterns; therefore, differentiation from not only metastatic liver tumors but also from hypervascular liver tumors including hepatocellular carcinoma was required. This case report highlights that although FFC can have a variety of imaging patterns; it can present arterial-phase hyperenhancement and washout patterns.

The Kurume Medical Journal
Kurume University (JP), St Mary's Hospital (JP), St. Mary’s Hospital (ZA)
Zero hunger
Openalex Percentile: Top 8%
Pancreatic and Hepatic Oncology Research
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Focal Fatty Change After Total Pancreatectomy Mimics Hypervascular Liver Tumor — Koichi Higaki, Keiichi Mitsuyama, et al. · The Kurume Medical Journal (2026) | TGRS Research Map | TGRS