Antibacterial Wound Dressing Enables Reliable Detection of Uric Acid in Exudates

Through the successful grafting of epoxypropyl dimethyl dodecyl ammonium chloride (EDDAC) onto bacterial cellulose (BC) and multiwalled carbon nanotube (CNT) surfaces, a novel and stable antibacterial wound dressing (BC‐EDDAC‐CNTs) was fabricated. Compared with bare BC membranes, BC‐EDDAC exhibited significantly enhanced antibacterial activity. Furthermore, a nonenzymatic uric acid (UA) sensor was constructed on the membrane surface via the electrodeposition of AuNPs, resulting in an antibacterial wound dressing with integrated UA‐sensing capability. In vitro evaluations further indicated high L929 cell viability (∼94%–95%), very low hemolysis (<0.5%), and effective bactericidal activity confirmed by Live/Dead staining. This multifunctional dressing enables simultaneous infection control and metabolic monitoring along a clinically relevant chronic wound management workflow, including passive exudate sampling, low‐volume analysis, and real‐time electrochemical readout.