An 11-Year-Old Athlete With Dynamic Stenosis of Coronary Artery Anomaly With Normal FFR-Dobutamine But Abnormal iFR-Dobutamine

Anomalous aortic origin of a right coronary artery (R-AAOCA) can cause stress-induced ischemia owing to dynamic stenosis of the intramural course. While fractional flow reserve during dobutamine challenge (FFRDobutamine) is the reference standard for hemodynamic assessment, specific scenarios favoring instantaneous wave-free ratio (iFR) over FFR remain unclear.

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Publication Details

Journal
JACC Case Reports
Published
2026-03-01
DOI
https://doi.org/10.1016/j.jaccas.2026.107028
Primary Topic
Coronary Artery Anomalies
Type
article
Field-Weighted Citation Impact
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article

An 11-Year-Old Athlete With Dynamic Stenosis of Coronary Artery Anomaly With Normal FFR-Dobutamine But Abnormal iFR-Dobutamine

Mr. Isaac Shiri, Ali Mohammad Mokhtari, Anselm W. Stark, Lorenz Räber et al.
JACC Case Reports
Coronary Artery Anomalies
article

An 11-Year-Old Athlete With Dynamic Stenosis of Coronary Artery Anomaly With Normal FFR-Dobutamine But Abnormal iFR-Dobutamine

Mr. Isaac Shiri, Ali Mohammad Mokhtari, Anselm W. Stark, Lorenz Räber, Ryota Kakizaki, Marius R. Bigler, Christoph Gräni, Matthias Siepe
article en

Abstract

Anomalous aortic origin of a right coronary artery (R-AAOCA) can cause stress-induced ischemia owing to dynamic stenosis of the intramural course. While fractional flow reserve during dobutamine challenge (FFRDobutamine) is the reference standard for hemodynamic assessment, specific scenarios favoring instantaneous wave-free ratio (iFR) over FFR remain unclear.

JACC Case ReportsVol. 31(12)
University of Bern (CH), University Hospital of Bern (CH)
Good health and well-being
Openalex Percentile: Top 8%
Coronary Artery Anomalies
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