Transportability to the European population of Efficacy of Belumosudil as Compared with Physician’s Choice of Best Available Therapy for The Treatment of Chronic Graft Versus Host Disease

In line with positive efficacy results observed in previous real-world evidence studies in US and European patients, findings from this transportability analysis indicate that the treatment-response pattern are similar in Europe compared to US and cGVHD patients treated with belumosudil would have significantly more clinical benefit compared to BAT in Europe.

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Publication Details

Journal
Transplantation and Cellular Therapy
Published
2026-03-01
DOI
https://doi.org/10.1016/j.jtct.2026.03.028
Primary Topic
Hematopoietic Stem Cell Transplantation
Type
article
Field-Weighted Citation Impact
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article

Transportability to the European population of Efficacy of Belumosudil as Compared with Physician’s Choice of Best Available Therapy for The Treatment of Chronic Graft Versus Host Disease

Aleksandr Lazaryan, Alexandra Koumas, Shaum Kabadi, E. K. Waller et al.
Transplantation and Cellular Therapy
Hematopoietic Stem Cell Transplantation
article

Transportability to the European population of Efficacy of Belumosudil as Compared with Physician’s Choice of Best Available Therapy for The Treatment of Chronic Graft Versus Host Disease

Aleksandr Lazaryan, Alexandra Koumas, Shaum Kabadi, E. K. Waller, Susan Gruber, Lauren Rota, Ekaterina Ponomareva, Aaron C. Logan, Charlie Nicholls, Mark van der Laan, Enkeleida Nikai, Daniel Wolff, David Michonneau, Catherine J. Lee, Francesca Bonifazi, Irfan Khan, Carlos Solano, Varun Mehra, Kevin Hall
article en

Abstract

In line with positive efficacy results observed in previous real-world evidence studies in US and European patients, findings from this transportability analysis indicate that the treatment-response pattern are similar in Europe compared to US and cGVHD patients treated with belumosudil would have significantly more clinical benefit compared to BAT in Europe.

Transplantation and Cellular Therapy
Emory Healthcare (US), Seattle Cancer Care Alliance (US), Emory University (US), Universitat de València (ES), Sanofi (France) (FR), Moffitt Cancer Center (US), University Hospital Regensburg (DE), Hospital Clínico Universitario de Valencia (ES), Piedmont Cancer Institute (US), Revolution Medicines (United States) (US), American Energy Technologies Co (United States) (US), Sanofi (United States) (US), Azienda USL di Bologna (IT), Hôpital Saint-Louis (FR), Sanofi (United Kingdom) (GB), King's College Hospital (GB), UCSF Helen Diller Family Comprehensive Cancer Center (US)
Zero hunger
Openalex Percentile: Top 7%
Hematopoietic Stem Cell Transplantation
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