Pathological Complete Response after Robot-Assisted Pulmonary Resection Following CDK4/6 Inhibitor–Combined Endocrine Therapy for Endobronchial Oligometastatic Breast Cancer: A Case Report

INTRODUCTION: Endobronchial metastasis from breast cancer is rare. Even in oligometastatic disease, systemic therapy remains the standard treatment, and the role of surgical resection is not well established. We report a case of endobronchial oligometastatic breast cancer that achieved pathological complete response (pCR) after endocrine therapy combined with a cyclin-dependent kinase 4/6 (CDK4/6) inhibitor, followed by pulmonary resection.

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Journal
Surgical Case Reports
Published
2026-01-01
DOI
https://doi.org/10.70352/scrj.cr.26-0010
Primary Topic
Advanced Breast Cancer Therapies
Type
article
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article

Pathological Complete Response after Robot-Assisted Pulmonary Resection Following CDK4/6 Inhibitor–Combined Endocrine Therapy for Endobronchial Oligometastatic Breast Cancer: A Case Report

Mariko Nishikawa, Chika Watanabe, Wataru Goto, Shinichiro Kashiwagi et al.
Surgical Case Reports
Advanced Breast Cancer Therapies
article

Pathological Complete Response after Robot-Assisted Pulmonary Resection Following CDK4/6 Inhibitor–Combined Endocrine Therapy for Endobronchial Oligometastatic Breast Cancer: A Case Report

Mariko Nishikawa, Chika Watanabe, Wataru Goto, Shinichiro Kashiwagi, Haruhito Kinoshita, TAMAMI MORISAKI, Koji Takada, Yukie Tauchi, Kenichi Kohashi, Hikari Nitahara, Kana Ogisawa
article en

Abstract

INTRODUCTION: Endobronchial metastasis from breast cancer is rare. Even in oligometastatic disease, systemic therapy remains the standard treatment, and the role of surgical resection is not well established. We report a case of endobronchial oligometastatic breast cancer that achieved pathological complete response (pCR) after endocrine therapy combined with a cyclin-dependent kinase 4/6 (CDK4/6) inhibitor, followed by pulmonary resection.

Surgical Case ReportsVol. 12(1)
Osaka City University (JP), Sumitomo Hospital (JP)
Good health and well-being
Openalex Percentile: Top 8%
Advanced Breast Cancer Therapies
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Pathological Complete Response after Robot-Assisted Pulmonary Resection Following CDK4/6 Inhibitor–Combined Endocrine Therapy for Endobronchial Oligometastatic Breast Cancer: A Case Report — Mariko Nishikawa, Chika Watanabe, et al. · Surgical Case Reports (2026) | TGRS Research Map | TGRS