Analysis of Biomarkers in Diabetic Foot Ulcer Patients With Dampness–Heat Syndrome Based on 4D‐DIA Proteomics Technology

To our knowledge, this is the first study to employ 4D-DIA proteomics on DFU-DHS. We identified four serum biomarkers (APOA1, LCAT, PLTP, and CETP) linked to dysregulated cholesterol metabolism in DFU-DHS patients, which show diagnostic potential and provide insights for integrating TCM syndrome differentiation with precision medicine.

Authors

Institutions

Publication Details

Journal
Journal of Diabetes Research
Published
2026-01-01
DOI
https://doi.org/10.1155/jdr/6604989
Primary Topic
Diabetic Foot Ulcer Assessment and Management
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Analysis of Biomarkers in Diabetic Foot Ulcer Patients With Dampness–Heat Syndrome Based on 4D‐DIA Proteomics Technology

Shiyu Wang, Mingmei Zhou, Jinlun Jiang, Cheng Zhao et al.
Journal of Diabetes Research
Diabetic Foot Ulcer Assessment and Management
article

Analysis of Biomarkers in Diabetic Foot Ulcer Patients With Dampness–Heat Syndrome Based on 4D‐DIA Proteomics Technology

Shiyu Wang, Mingmei Zhou, Jinlun Jiang, Cheng Zhao, Jiawei Feng, Yiming Ni
article en

Abstract

To our knowledge, this is the first study to employ 4D-DIA proteomics on DFU-DHS. We identified four serum biomarkers (APOA1, LCAT, PLTP, and CETP) linked to dysregulated cholesterol metabolism in DFU-DHS patients, which show diagnostic potential and provide insights for integrating TCM syndrome differentiation with precision medicine.

Journal of Diabetes ResearchVol. 2026(1)
Shanghai University of Traditional Chinese Medicine (CN), Shanghai Traditional Chinese Medicine Hospital (CN)
Good health and well-being
Openalex Percentile: Top 9%
Diabetic Foot Ulcer Assessment and Management
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.