Angiopathie amyloïde cérébrale inflammatoire et immunothérapies anti-amyloïde

Cerebral amyloid angiopathy can be complicated by an inflammatory form known as CAA-ri (cerebral amyloid angiopathy-related inflammation), a rare but sometimes severe condition whose prognosis is improved by early diagnosis and treatment. CAA-ri shares physiopathological, clinical and radiological features with amyloid-related imaging abnormalities (ARIA), a complication observed during the development of novel anti-amyloid immunotherapies for Alzheimer's disease (AD). These ARIA are more frequent and severe in patients with CAA, requiring particular attention given the significant overlap between AD and this pathology. This article aims to raise awareness and improve recognition of these entities associated with amyloid deposition.