Transcriptomic profiling of fecal aspirates as a tool for prediction of endoscopic inflammation in small bowel Crohn’s disease

Transcriptomic profiling of rectal fecal aspirates reliably detects small bowel inflammation and identifies specific immune pathways in asymptomatic CD. The resulting models offer potential biomarkers for CD diagnosis and monitoring.

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Publication Details

Journal
Journal of Crohn s and Colitis
Published
2026-03-01
DOI
https://doi.org/10.1093/ecco-jcc/jjag026
Primary Topic
Inflammatory Bowel Disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Transcriptomic profiling of fecal aspirates as a tool for prediction of endoscopic inflammation in small bowel Crohn’s disease

Miri Yavzori, Tal Meningher, Doron Yablecovitch, Ella Fudim et al.
Journal of Crohn s and Colitis
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Transcriptomic profiling of fecal aspirates as a tool for prediction of endoscopic inflammation in small bowel Crohn’s disease

Miri Yavzori, Tal Meningher, Doron Yablecovitch, Ella Fudim, Bella Ungar, S Ben-Horin, Omri Nayshool, Orit Picard, Adi Talan-Asher, Uri Kopylov, Bozena Borenstein, Orel Finkel, Biana Fritz
article en

Abstract

Transcriptomic profiling of rectal fecal aspirates reliably detects small bowel inflammation and identifies specific immune pathways in asymptomatic CD. The resulting models offer potential biomarkers for CD diagnosis and monitoring.

Journal of Crohn s and ColitisVol. 20(3)
Tel Aviv University (IL), Sheba Medical Center (IL)
Reduced inequalities, Peace, Justice and strong institutions
Openalex Percentile: Top 8%
Inflammatory Bowel Disease
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