Anticandidal Efficacy of Complete Denture Cleansers of 0.20% Sodium Hypochlorite Versus Triphala Churna in Diabetic and Nondiabetic Patients: A Randomized Clinical Study

Aim The aim of this randomized clinical study was to compare the anticandidal efficacy of 0.20% sodium hypochlorite and Triphala churna in diabetic and nondiabetic complete denture wearers. Materials and Methods In this randomized clinical study, 40 participants were allocated into four subgroups ( n = 10 each): diabetic participants using sodium hypochlorite (Group 1A), diabetic participants using Triphala churna (Group 1B), nondiabetic participants using sodium hypochlorite (Group 2A), and nondiabetic participants using Triphala churna (Group 2B). Biofilm samples were collected from the intaglio surface of maxillary dentures at baseline and after 21 days of daily immersion. Candida colony‐forming units (CFU/mL) were quantified using Sabouraud Dextrose Agar and confirmed using HiCrome Candida Differential Agar . Statistical analysis included paired and unpaired t ‐tests and two‐way repeated measures ANOVA with Bonferroni post hoc tests. Results All subgroups demonstrated a significant reduction in CFU counts after 21 days ( p < 0.01). Two‐way repeated measures ANOVA revealed a significant effect of time ( p < 0.001), while no significant interaction was observed between cleanser type and diabetic status ( p > 0.05). Neither sodium hypochlorite nor Triphala churna showed superiority over the other. Conclusion Both 0.20% sodium hypochlorite and Triphala churna effectively reduced Candida colonization on complete dentures in diabetic and nondiabetic individuals. Triphala churna may serve as a safe and cost‐effective herbal alternative for routine denture hygiene, particularly for patients seeking nonchemical cleansing options.