Advancements in Accelerator and Beam Delivery Technology

In this article, we review the development of accelerator and beam delivery technology for particle therapy. The working principles of accelerators, encompassing isochronous cyclotrons, synchrocyclotrons and synchrotrons, and recent advancements in other accelerator technology, are presented. For beam delivery technology, we focus on pencil beam scanning (PBS) for intensity modulated proton therapy (IMPT). In addition, we incorporate aspects of proton arc therapy, ultrahigh-dose rate FLASH therapy, and motion management for PBS beam delivery. Last, we have discussions on imaging guidance for particle therapy treatment delivery, upright patient positioning, and online adaptive therapy.

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Publication Details

Journal
The Cancer Journal
Published
2026-03-01
DOI
https://doi.org/10.1097/ppo.0000000000000817
Primary Topic
Radiation Therapy and Dosimetry
Type
article
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0.00
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article

Advancements in Accelerator and Beam Delivery Technology

Yoshifumi Hojo, Falk Poenisch, Fahed Alsanea, Yuting Li et al.
The Cancer Journal
Radiation Therapy and Dosimetry
article

Advancements in Accelerator and Beam Delivery Technology

Yoshifumi Hojo, Falk Poenisch, Fahed Alsanea, Yuting Li, Ming Yang, Thomas J. Whitaker, Narayan Sahoo, Xiaodong Zhang, Xiaorong Ronald Zhu, Mei Chen
article en

Abstract

In this article, we review the development of accelerator and beam delivery technology for particle therapy. The working principles of accelerators, encompassing isochronous cyclotrons, synchrocyclotrons and synchrotrons, and recent advancements in other accelerator technology, are presented. For beam delivery technology, we focus on pencil beam scanning (PBS) for intensity modulated proton therapy (IMPT). In addition, we incorporate aspects of proton arc therapy, ultrahigh-dose rate FLASH therapy, and motion management for PBS beam delivery. Last, we have discussions on imaging guidance for particle therapy treatment delivery, upright patient positioning, and online adaptive therapy.

The Cancer JournalVol. 32(2)
The University of Texas MD Anderson Cancer Center (US)
Openalex Percentile: Top 8%
Radiation Therapy and Dosimetry
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