Quadricuspid Aortic Valve With Severe Aortic Regurgitation and Coronary Artery Disease: A Rare Association

Quadricuspid aortic valve (QAV) is a rare congenital anomaly. There are various hypotheses regarding the embryological development of a QAV. Patients are usually diagnosed at a mean age of 50.7 years with a male preponderance, and surgery in the form of an aortic valve repair or replacement is usually the treatment strategy. There are various congenital cardiac defects and anomalies associated with a QAV, which can be coronary artery abnormalities, ASD, VSD, and so on. We are reporting a 51‐year‐old female patient who was incidentally diagnosed with a quadricuspid aortic valve and progressive aortic regurgitation with coronary artery disease. This case illustrates an association of QAV with atherosclerotic disease, which is a distinct and rarely reported finding.

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Publication Details

Journal
Case Reports in Cardiology
Published
2026-01-01
DOI
https://doi.org/10.1155/cric/4242498
Primary Topic
Aortic Disease and Treatment Approaches
Type
article
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article

Quadricuspid Aortic Valve With Severe Aortic Regurgitation and Coronary Artery Disease: A Rare Association

Asher George Joseph, Vineetha Malayil, Isaac S Kadir, Sujata Anipindi
Case Reports in Cardiology
Aortic Disease and Treatment Approaches
article

Quadricuspid Aortic Valve With Severe Aortic Regurgitation and Coronary Artery Disease: A Rare Association

Asher George Joseph, Vineetha Malayil, Isaac S Kadir, Sujata Anipindi
article en

Abstract

Quadricuspid aortic valve (QAV) is a rare congenital anomaly. There are various hypotheses regarding the embryological development of a QAV. Patients are usually diagnosed at a mean age of 50.7 years with a male preponderance, and surgery in the form of an aortic valve repair or replacement is usually the treatment strategy. There are various congenital cardiac defects and anomalies associated with a QAV, which can be coronary artery abnormalities, ASD, VSD, and so on. We are reporting a 51‐year‐old female patient who was incidentally diagnosed with a quadricuspid aortic valve and progressive aortic regurgitation with coronary artery disease. This case illustrates an association of QAV with atherosclerotic disease, which is a distinct and rarely reported finding.

Case Reports in CardiologyVol. 2026(1)
P. D. Hinduja Hospital and Medical Research Centre (IN), Wythenshawe Hospital (GB)
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Openalex Percentile: Top 8%
Aortic Disease and Treatment Approaches
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Quadricuspid Aortic Valve With Severe Aortic Regurgitation and Coronary Artery Disease: A Rare Association — Asher George Joseph, Vineetha Malayil, et al. · Case Reports in Cardiology (2026) | TGRS Research Map | TGRS