Efficacy and Safety of Cerebrolysin as an Adjunct to Mechanical Thrombectomy in Acute Ischemic Stroke: A Systematic Review and Meta‐Analysis of Observational Studies
Cerebrolysin shows promise as a useful neuroprotective treatment in stroke care by dramatically improving functional recovery, reducing symptomatic intracranial bleeding, and lowering mortality in acute ischemic stroke patients when used in conjunction with mechanical thrombectomy. Nonetheless, these conclusions are derived from only three observational studies with small sample sizes, which limits the robustness and generalizability of the findings. Further large-scale randomized trials are warranted to confirm these effects.
Authors
- Amjad Ali
- Fatima Sajjad (ORCID: https://orcid.org/0009-0009-8861-0367)
- Noor Fatima (ORCID: https://orcid.org/0000-0002-9245-7352)
- Muhammad Abdullah (ORCID: https://orcid.org/0000-0003-0069-0833)
- Adam Saeed
- Iqra Shahid (ORCID: https://orcid.org/0009-0009-7188-1312)
- Laiba Ali Khan
- Kamil Ahmad Kamil (ORCID: https://orcid.org/0009-0000-8208-0689)
- Umama Alam
- Rida Khan Hoti
- Shahbaz Khan
- Abdullah Afridi
- Suleman Khan
- Sajjad GhanimAl‐Badri
- Muhammad Abu Bakkar
- Ayesha Arshad
Institutions
- Bacha Khan University (PK)
- King Edward Medical University (PK)
- Khyber Medical College (PK)
- Khyber Teaching Hospital (PK)
- Hayatabad Medical Complex (PK)
- Kandahar University (AF)
- Dow University of Health Sciences (PK)
- University of Kerbala (IQ)
- University of Warith Al-Anbiyaa
Publication Details
- Journal
- Brain and Behavior
- Published
- 2026-03-01
- DOI
- https://doi.org/10.1002/brb3.71252
- Primary Topic
- Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00