Nonanemic Iron Deficiency

Exercise intolerance in athletes is often attributed to cardiopulmonary or autonomic causes; however, nonanemic iron deficiency is a common and under-recognized contributor that may hinder aerobic adaptation. Ferritin thresholds used in general populations do not reflect athletes' higher physiological iron requirements.

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Publication Details

Journal
JACC Case Reports
Published
2026-03-01
DOI
https://doi.org/10.1016/j.jaccas.2026.107376
Primary Topic
Iron Metabolism and Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Nonanemic Iron Deficiency

Eugene H. Chung, N. Lewis, James Sawalla Guseh, Gianmichel D. Corrado et al.
JACC Case Reports
Iron Metabolism and Disorders
article

Nonanemic Iron Deficiency

Eugene H. Chung, N. Lewis, James Sawalla Guseh, Gianmichel D. Corrado, Aaron L. Baggish, Erin Orchard, Sarah M.E. McErlean, Katie M. Stewart, Loba Alam, Timothy W. Churchill
article en

Abstract

Exercise intolerance in athletes is often attributed to cardiopulmonary or autonomic causes; however, nonanemic iron deficiency is a common and under-recognized contributor that may hinder aerobic adaptation. Ferritin thresholds used in general populations do not reflect athletes' higher physiological iron requirements.

JACC Case ReportsVol. 31(12)
Brigham and Women's Hospital (US), Centre Hospitalier Universitaire Vaudois (CH), Massachusetts General Hospital (US), University of Lausanne (CH), Icahn School of Medicine at Mount Sinai (US)
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Openalex Percentile: Top 8%
Iron Metabolism and Disorders
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