D-Galactose-conjugated pyrimidine thioureas as potent antimicrobial agents: rapid green synthesis, structure-activity relationships and molecular modelling

A series of D-galactose-conjugated pyrimidine-based thioureas 8a-l was efficiently synthesized using an environmentally benign ionic liquid-microwave protocol. Optimal conditions employing [BMIM][BF4] under microwave irradiation (100 W) afforded excellent yields (up...

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Publication Details

Journal
RSC Medicinal Chemistry
Published
2026-01-01
DOI
https://doi.org/10.1039/d6md00026f
Primary Topic
Microwave-Assisted Synthesis and Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

D-Galactose-conjugated pyrimidine thioureas as potent antimicrobial agents: rapid green synthesis, structure-activity relationships and molecular modelling

Vũ Ngọc Toán, Dương Ngọc Toàn, Hoàng Thi Kim Van, Nguyen Dinh Thanh et al.
RSC Medicinal Chemistry
Microwave-Assisted Synthesis and Applications
article

D-Galactose-conjugated pyrimidine thioureas as potent antimicrobial agents: rapid green synthesis, structure-activity relationships and molecular modelling

Vũ Ngọc Toán, Dương Ngọc Toàn, Hoàng Thi Kim Van, Nguyen Dinh Thanh, Nguyen Minh Tri, Ngo Hong Anh Thu
article en

Abstract

A series of D-galactose-conjugated pyrimidine-based thioureas 8a-l was efficiently synthesized using an environmentally benign ionic liquid-microwave protocol. Optimal conditions employing [BMIM][BF4] under microwave irradiation (100 W) afforded excellent yields (up...

RSC Medicinal Chemistry
Openalex Percentile: Top 8%
Microwave-Assisted Synthesis and Applications
DOISourceOpenAlex
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D-Galactose-conjugated pyrimidine thioureas as potent antimicrobial agents: rapid green synthesis, structure-activity relationships and molecular modelling — Vũ Ngọc Toán, Dương Ngọc Toàn, et al. · RSC Medicinal Chemistry (2026) | TGRS Research Map | TGRS