Midterm Outcomes of Combination Therapy With Immune Checkpoint Inhibitors and <scp>VEGFR</scp> ‐ <scp>TKIs</scp> in Real‐World Patients With Advanced Renal Cell Carcinoma

With a minimum of 3 years of follow-up, IO-TKI demonstrated feasible effectiveness and manageable safety in patients with advanced RCC in the real world. More effective treatment strategies and novel therapeutic targets are needed for patients with non-clear-cell RCC.

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Publication Details

Journal
International Journal of Urology
Published
2026-03-01
DOI
https://doi.org/10.1111/iju.70444
Primary Topic
Renal cell carcinoma treatment
Type
article
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article

Midterm Outcomes of Combination Therapy With Immune Checkpoint Inhibitors and VEGFR ‐ TKIs in Real‐World Patients With Advanced Renal Cell Carcinoma

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Renal cell carcinoma treatment
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Midterm Outcomes of Combination Therapy With Immune Checkpoint Inhibitors and VEGFR ‐ TKIs in Real‐World Patients With Advanced Renal Cell Carcinoma

Nanaka Katsurayama, Hiroaki Shimmura, Kazuhiko Yoshida, Hironori Fukuda, Junpei Iizuka, Yuki Nemoto, Takayuki Nakayama, Shinsuke Mizoguchi, Tsunenori Kondo, Yasunobu Hashimoto, Hiroki Ishihara, Toshio Takagi
article en

Abstract

With a minimum of 3 years of follow-up, IO-TKI demonstrated feasible effectiveness and manageable safety in patients with advanced RCC in the real world. More effective treatment strategies and novel therapeutic targets are needed for patients with non-clear-cell RCC.

International Journal of UrologyVol. 33(3)
Jyoban Hospital of Tokiwa Foundation (JP), Tokyo Women's Medical University Adachi Medical Center (JP), Tokyo Women's Medical University (JP), Noguchi Hospital (JP), Saiseikai Ibaraki Hospital (JP)
Openalex Percentile: Top 8%
Renal cell carcinoma treatment
DOISourceOpenAlex
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