Concordance of Circulating Tumor DNA, Primary and Metastatic Tissue DNA, and Immunohistochemistry in Gastroesophageal Carcinoma
ctDNA testing demonstrates high concordance with tDNA and IHC and offers faster turnaround. Given its minimally invasive nature and strong concordance with tissue-based testing, ctDNA is a reliable tool for genomic profiling and longitudinal monitoring in GEC.
Authors
- Hesham Sheashaa
- Harry H. Yoon
- Hani M. Babiker (ORCID: https://orcid.org/0000-0002-9368-6296)
- Daniel H. Ahn (ORCID: https://orcid.org/0000-0002-0161-4018)
- Þorvarður R. Hálfdánarson (ORCID: https://orcid.org/0000-0001-8460-1257)
- Umair Majeed (ORCID: https://orcid.org/0000-0001-5839-9905)
- Fares Jamal
- Mohamad Bassam Sonbol
- Oudai Sahwan (ORCID: https://orcid.org/0000-0001-9837-0891)
- Seyi Abidoye
- Abdullah Alsulaiman
- Zhaohui Jin
- Jeremy Jones
- Tanios Bekaii-Saab
- Mojun Zhu
- Mitesh Borad (ORCID: https://orcid.org/0000-0003-2700-2658)
- Jason S. Starr
- Christina Wu
Institutions
- Mount Sinai Health System (US)
- Valley Health System (US)
- Mayo Clinic in Arizona (US)
- Mayo Clinic Hospital (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- JCO Precision Oncology
- Published
- 2026-03-01
- DOI
- https://doi.org/10.1200/po-25-01194
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00