Dual‐Light‐Primed GSH‐Scavenging Lipid Hybrid Nanoplatform for Cascade‐Activated Photodynamic Therapy (Small 18/2026)
Photodynamic Therapy This cover illustrates a lipid-hybridized nanoplatform (CSA-psICG/BdTT-BNBE) for cascade-activated photodynamic therapy. Guided by CSA–CD44 targeting, the system responds to dual-light irradiation (NIR and white light), triggering glutathione depletion and amplified ROS generation. This strategy enables spatiotemporally controlled activation and enhances therapeutic efficacy against tumors. More in the Research Article (e12546), Jeeyeon Lee, Jae-Young Lee, and co-workers.
Authors
- Hyeonwoo Lim
- S Lee
- T. J. Kim (ORCID: https://orcid.org/0000-0001-8336-2434)
- Jiyeon Kim (ORCID: https://orcid.org/0000-0003-4799-050X)
- Tae‐Yong Kim (ORCID: https://orcid.org/0000-0002-3930-6766)
- Le Bich Hang Pham
- Ka‐Young Lim
- JungHun Kang
- Jeeyeon Lee
- So‐Yeol Yoo
- Sang Min Lee
- Jae‐Young Lee
Institutions
- Seoul National University (KR)
- National University (SD)
Publication Details
- Journal
- Small
- Published
- 2026-03-01
- DOI
- https://doi.org/10.1002/smll.73028
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00